Biomedical

Novel perspectives in mammalian copper metabolism through the use of genome-wide approaches

Type of publication: 
Matching Publication
Authors: 
P.A. Muller, L.W. Klomp
Published in: 
American Journal of Clinical Nutrition
Date of publication: 
2008/09
Status of the publication: 
Published/accepted
Theme: 
Theme: 
Pages: 
2008; 88 (3): 821S-825S

Sequencing and functional assessment of hPXR (NR1I2) variants in intrahepatic cholestasis of pregnancy

Type of publication: 
Matching Publication
Authors: 
B.M. Owen, S.W. van Mil, M. Boudjelal, I. McLay, W. Cairns, E. Elias, R. White, C. Williamson, P.H. Dixon
Published in: 
Xenobiotica
Date of publication: 
2008/10
Status of the publication: 
Published/accepted
Theme: 
Theme: 
Pages: 
2008; 38 (10): 1289-1297
DOI: 
10.1080/00498250802426114

Elevated cholesterol precursors other than cholestanol can also be a hallmark for CTX

Type of publication: 
Matching Publication
Authors: 
M.G. de Sain-van der Velden, A. Verrips, B.H. Prinsen, M. de Barse, R. Berger, G. Visser
Authors from the NMC: 
Published in: 
Journal of Inherited Metabolic Disease
Date of publication: 
2008/12
Status of the publication: 
Published/accepted
Theme: 
Theme: 
Pages: 
2008; 31 Suppl 2: S387-393
DOI: 
10.1007/s10545-008-0963-1

Role of transition metals in the pathogenesis of amyotrophic lateral sclerosis

Type of publication: 
Matching Publication
Authors: 
W.I. Vonk, L.W. Klomp
Published in: 
Biochemical Society Transactions
Date of publication: 
2008/12
Status of the publication: 
Published/accepted
Theme: 
Theme: 
Pages: 
2008; 36 (Pt 6):1322-1328
DOI: 
10.1042/BST0361322

Plasma acylcarnitine and fatty acid profiles during exercise and training in Standardbreds

Type of publication: 
Matching Publication
Authors: 
C.M. Westermann, B. Dorland, M.G. de Sain-van der Velden, I.D. Wijnberg, E. van Breda, E. de Graaf-Roelfsema, H.A. Keizer, J.H. van der Kolk
Authors from the NMC: 
Published in: 
American Journal of Veterinary Research
Date of publication: 
2008/11
Status of the publication: 
Published/accepted
Theme: 

OBJECTIVE:

To evaluate alterations in skeletal muscle carnitine metabolism during exercise and training by measuring changes in plasma acylcarnitine concentrations in Standardbreds.

ANIMALS:

10 Standardbred geldings with a mean +/- SD age of 20 +/- 2 months and weight of 384 +/- 42 kg.

Theme: 
Pages: 
2008; 69 (11): 1469-1475
DOI: 
10.2460/ajvr.69.11.1469

Systems pharmacology, biomarkers, and biomolecular networks

Type of publication: 
Matching Publication
Authors: 
A.S. Adourian, T.N. Plasterer, R. Balasubramanian, E.G. Jennings, S. Wang, S. Martin, J. van der Greef, R.N. McBurney, P. Muntendam, N.B. Afeyan
Authors from the NMC: 
Published in: 
Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools
Date of publication: 
2008/07
Status of the publication: 
Published/accepted
Theme: 
Publisher: 
John Wiley & Sons
Theme: 
DOI: 
10.1002/9780470431818.ch4

Correlation network analysis for data integration and biomarker selection

Type of publication: 
Matching Publication
Authors: 
A. Adourian, E. Jennings, R. Balasubramanian and others
Published in: 
Molecular Biosystems
Date of publication: 
2008/03
Status of the publication: 
Published/accepted
Theme: 
Theme: 
Pages: 
2008; 4 (3): 249-259
DOI: 
10.1039/b708489g

Imaging of ultra-weak photon emission in a rheumatoid arthritis mouse model

Type of publication: 
NMC Publication
Authors: 
E.P.A. van Wijk, M. Kobayashi, R. van Wijk, J. van der Greef
Authors from the NMC: 
Published in: 
PLoS ONE
Date of publication: 
2013/12
Status of the publication: 
Published/accepted
Theme: 
Source: 
Sino Dutch Institute for Preventive and Personalized Medicine

Ultra-weak photon emission (UPE) of a living system received scientific attention because of its potential for monitoring increased levels of reactive oxygen species (ROS) in the pathogenesis of rheumatoid arthritis (RA). In this study, a highly sensitive cryogenic charge-coupled device (CCD) camera was used to monitor in a RA mouse model the photon emission both without and with luminol. For that purpose, arthritis was induced in mice utilizing a repeated co-administration of type II collagen with lipopolysaccharide.

Theme: 
Pages: 
2013; 8 (12): e84579
DOI: 
10.1371/journal.pone.0084579

The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor regulates peroxisome proliferator-activated receptor gamma-dependent adipocyte differentiation

Type of publication: 
Matching Publication
Authors: 
K.M. Dreijerink, R.A. Varier, O. van Beekum, E.H. Jeninga, J.W. Höppener, C.J. Lips, J.A. Kummer, E. Kalkhoven, H.T.M. Timmers
Authors from the NMC: 
Published in: 
Molecular & Cellular Biology
Date of publication: 
2009/09
Status of the publication: 
Published/accepted
Theme: 
Theme: 
Pages: 
2009; 29 (18): 5060-5069
DOI: 
10.1128/MCB.01001-08

Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity

Type of publication: 
Matching Publication
Authors: 
P. Hallenborg, C. Jørgensen, R.K. Petersen, S. Feddersen, P. Araujo, P. Markt, T. Langer, G. Furstenberger, P. Krieg, A. Koppen, E. Kalkhoven, L. Madsen, K. Kristiansen
Authors from the NMC: 
Published in: 
Molecular & Cellular Biology
Date of publication: 
2010/08
Status of the publication: 
Published/accepted
Theme: 
Theme: 
Pages: 
2010; 30 (16): 4077-4091
DOI: 
10.1128/MCB.01806-08