Industrial biotechnology

The effect of environmental conditions on extracellular protease activity in controlled fermentations of Aspergillus niger

Type of publication: 
Matching Publication
Authors: 
M. Braaksma, A.K. Smilde, M.J. van der Werf, P.J. Punt
Authors from the NMC: 
Published in: 
Microbiology
Date of publication: 
2009/10
Status of the publication: 
Published/accepted
Pages: 
2009; 155 (Pt 10): 3430-3439
DOI: 
10.1099/mic.0.031062-0
Publication data (text): 
2009

Industrial biotechnology

Type of theme: 
Associate
Short description: 
As the central item of the Industrial Biotechnology program, we have chosen to use the metabolomics infrastructure present at TU Delft, TNO, NMC and DSM to study the influence of the extracellular metabolome on the intracellular metabolome and vice versa. As the yeast Saccharomyces is the most widely used microorganism in industrial biotechnology this has been chosen in both projects.

The central topic of the Industrial biotech program, consisting of two PhD projects, is the influence of the extracellular metabolome on the intracellular metabolome and vice versa. At the start of NMC, with its main focus on human applications, two organisations in the Netherlands (TU Delft and TNO) already had a sound track record with respect to metabolomics research in Industrial Biotechnology applications.

Theme leader: