Biomedical

Quality and safety of Chinese herbal medicines guided by a systems biology perspective

Type of publication: 
NMC Publication
Authors: 
J. Wang, R. van der Heijden, S. Spruit, T. Hankemeier, K. Chan, J. van der Greef, G. Xu, M. Wang
Authors from the NMC: 
Published in: 
Journal of Ethnopharmacology
Date of publication: 
2009/10
Status of the publication: 
Published/accepted
Theme: 
Source: 
Sino Dutch Institute for Preventive and Personalized Medicine
Theme: 
Pages: 
2009; 126 (1): 31-41
DOI: 
10.1016/j.jep.2009.07.040
Publication data (text): 
2009

Systems toxiology study of doxorubicin on rats using ultra performance liquid chromatography coupled with mass spectrometry based metabolomics

Type of publication: 
NMC Publication
Authors: 
J. Wang, T. Reijmers, L. Chen, R. van der Hoeve, M. Wang, S. Peng, T. Hankemeier, G. Zu, J. van der Greef
Published in: 
Metabolomics
Date of publication: 
2009/12
Status of the publication: 
Published/accepted
Theme: 
Source: 
Sino Dutch Institute for Preventive and Personalized Medicine
Theme: 
Pages: 
2009; 5 (4): 407-418
DOI: 
10.1007/s11306-009-0165-3
Publication data (text): 
2009

Commentary: "A systems view on the future of medicine: Inspiration from Chinese medicine?"

Type of publication: 
Matching Publication
Authors: 
R. Verpoorte, D. Crommelin, M. Danhof, L.J.W.J. Gilissen, H. Schuitmaker, J. van der Greef, R.F. Witkamp
Authors from the NMC: 
Published in: 
Journal of Ethnopharmacology
Date of publication: 
2009/01
Status of the publication: 
Published/accepted
Theme: 
Source: 
Sino Dutch Institute for Preventive and Personalized Medicine
Theme: 
Pages: 
2009; 121 (3): 479–481
DOI: 
10.1016/j.jep.2008.11.005
Publication data (text): 
2009

Separation and identification of malonyl-ginsenosides in white ginseng using HPLC-LTQ-FTMS

Type of publication: 
Matching Publication
Authors: 
H. Kong, M. Wang, R. van der Heijden, J. van der Greef , T. Hankemeier, G. Xu
Authors from the NMC: 
Published in: 
World Science and Technology (Modernization of Traditional Chinese Medicine and Materia Medica)
Date of publication: 
2009/01
Status of the publication: 
Published/accepted
Theme: 
Source: 
Sino Dutch Institute for Preventive and Personalized Medicine
Theme: 
Publication data (text): 
2009

Systems biology-based diagnostic principles as pillars of the bridge between Chinese and Western medicine

Type of publication: 
NMC Publication
Authors: 
J. van der Greef, H. van Wietmarschen, J. Schroën, M. Wang, T. Hankemeier, G. Xu
Published in: 
Planta Medica
Date of publication: 
2010/12
Status of the publication: 
Published/accepted
Theme: 
Source: 
Sino Dutch Institute for Preventive and Personalized Medicine

Innovative systems approaches to develop medicine and health care are emerging from the integration of Chinese and Western medicine strategies, philosophies and practices. The two medical systems are highly complementary as the reductionist aspects of Western medicine are favourable in acute disease situations and the holistic aspects of Chinese medicine offer more opportunities in chronic conditions and for prevention.

Theme: 
Pages: 
2010; 76 (17): 2036-2047
DOI: 
10.1055/s-0030-1250450
Publication data (text): 
2010

Topical formulation containing natural oligomeric proanthocyanidins (OPCS) reduces UV-induced oxidative stress in skin as assessed by ultra-weak photon emission (UPE)

Type of publication: 
NMC Publication
Authors: 
R. van Wijk, S. Bosman, G. Achanta, E.P.A. van Wijk
Authors from the NMC: 
Published in: 
European Journal of Integrative Medicine
Date of publication: 
2009/12
Status of the publication: 
Published/accepted
Theme: 
Theme: 
Pages: 
2009; 1 (4): 192
DOI: 
10.1016/j.eujim.2009.08.098
Publication data (text): 
2009

Human ultraweak photon emission and the yin yang concept of Chinese medicine

Type of publication: 
NMC Publication
Authors: 
R. van Wijk, J. van der Greef, E.P.A. van Wijk
Authors from the NMC: 
Published in: 
Journal of Acupuncture and Meridian Studies
Date of publication: 
2010/12
Status of the publication: 
Published/accepted
Theme: 
Source: 
Sino Dutch Institute for Preventive and Personalized Medicine

The relationship between connective tissue and meridian function is discussed in terms of energy transmission. The network of hydrogen-bonded water molecules interspersed within the collagen fibrillar matrix is especially significant for both the sensitivity of connective tissue to weak signals of mechanical pressure, heat, or electricity and the electrical intercommunication that may correlate with the meridian acupuncture system. Special electromagnetic properties of connective tissue have similar collective properties of ultraweak photon emission.

Theme: 
Pages: 
2010; 3 (4): 221-231
DOI: 
10.1016/S2005-2901(10)60041-6
Publication data (text): 
2010

Using ultra-weak photon emission to determine the effect of oligomeric proanthocyanidins on oxidative stress of human skin

Type of publication: 
NMC Publication
Authors: 
E.P.A. van Wijk, R. van Wijk, S. Bosman
Authors from the NMC: 
Published in: 
Journal of Photochemistry and Photobiology B
Date of publication: 
2010/03
Status of the publication: 
Published/accepted
Theme: 

Exposure of skin to ultraviolet (UV) radiation triggers oxidative stress in skin tissue that can lead to erythema, early skin aging or even cancer. It is suggested that oligomeric proanthocyanidins (OPCs), phytonutrients that belong to the polyphenol family have an anti-oxidant/anti-inflammatory activity on the skin. Measuring ultra-weak photon emission (UPE) is a non-invasive, fairly-sensitive and convenient technique for continuously monitoring oxidative stress.

Theme: 
Pages: 
2010; 98 (3): 199-206
DOI: 
10.1016/j.jphotobiol.2010.01.003
Publication data (text): 
2010

Statistical analysis of the spontaneously emitted photon signals from palm and dorsal sides of both hands in human subjects

Type of publication: 
NMC Publication
Authors: 
E.P.A. van Wijk, R. van Wijk, R. Bajpai, J. van der Greef
Authors from the NMC: 
Published in: 
Journal of Photochemistry and Photobiology B
Date of publication: 
2010/06
Status of the publication: 
Published/accepted
Theme: 

Photon signals emitted spontaneously from dorsal and palm sides of both hands were recorded using 6000 time windows of size T=50 ms in 50 healthy human subjects. These photon signals demonstrated universal behaviour by variance and mean. The data sets for larger time windows up to T=50s were obtained by merging the data recorded with T=50 ms. The behaviour of Fano factor regarding different window sizes was investigated. The Fano factor hovered around one in signals up to T=3s and increased slowly with the increase in window size.

Theme: 
Pages: 
2010; 99 (3): 133-143
DOI: 
10.1016/j.jphotobiol.2010.03.008
Publication data (text): 
2010

Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study

Type of publication: 
Matching Publication
Authors: 
M.J. van Erk, S. Wopereis, C.M. Rubingh, T. van Vliet, E. Verheij, N.H.P. Cnubben, T.L. Pedersen, J.W. Newman, A.K. Smilde, J. van der Greef, H.F.J. Hendriks, B. van Ommen
Published in: 
BMC Medical Genomics
Date of publication: 
2010/02
Status of the publication: 
Published/accepted
Theme: 

BACKGROUND:

Chronic systemic low-grade inflammation in obese subjects is associated with health complications including cardiovascular diseases, insulin resistance and diabetes. Reducing inflammatory responses may reduce these risks. However, available markers of inflammatory status inadequately describe the complexity of metabolic responses to mild anti-inflammatory therapy.

Theme: 
Pages: 
2010; 3: 5
DOI: 
10.1186/1755-8794-3-5
Publication data (text): 
2010